Publications

2026

• Bariboloka K, Serrano-Saenz S, Savcigil Deniz Pinar, Spöck S, Poss R, Schreurs L D, Löber J, Serin N, JValiulis J, Nugraha K, Gangarossa G, Lütz A, Reese R, Klein S, Enssle J C, Buettner R, Kashkar H, Peifer M, Chapuy B, Knittel G, Labi V, Villunger A, Nguyen P H, Scheich S, Oellerich T, Walczak H, Flümann R, Jachimowicz R D, Hallek M, Reinhardt H C, Annibaldi A. Expression of cFLIP in B cells is essential for diffuse large B cell lymphoma pathogenesis. Blood doi: 10.1182/blood.2026033320

2025

• Oda H, Annibaldi A, Kastner DL, Aksentijevich I. (2025). Genetic Regulation of Cell Death: Insights from Autoinflammatory Diseases. Annual Reviews of Immunology Apr;43(1):313-342. https://doi.org/10.1146/annurev-immunol-090222-105848
• Hildebrandt X, Veli Ö, Hyoubi A, Zinngrebe J, Abdallah AT, Rodefeld J, Hoffmann A, Gardeweg L, Kaya Ö, Wagner E, Lindhorst A, Poggenberg M, Wang Y, Dimmler J, Schillings J, Koci P, Bonechi F, Capuccino LV, Kiefer C, Kelepouras K, Ghosh A, Noé F, Wolfrum C, Singer M, Liccardi G, Luedde T, Yavas A, Ghallab A, Hengstler JG, Antczak P, Gericke M, Winkels H, Blüher M, Walczak H, Annibaldi A, Fischer-Posovszky P, Peltzer N. Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome. Sci Adv. 2025 Sep 19;11(38):eadw2539. doi: 10.1126/sciadv.adw2539. Epub 2025 Sep 17.
• Sakthivelu V, Schmitt A, Odenthal F, Ndoci K, Touet M, Shaib AH, Chihab A, Wani GA, Nieper P, Hartmann GG, Pintelon I, Kisis I, Boecker M, Eckert NM, Iannicelli Caiaffa M, Ibruli O, Weber J, Maresch R, Bebber CM, Chitsaz A, Lütz A, Kim Alves Carpinteiro M, Morris KM, Franchino CA, Benz J, Pérez-Revuelta L, Soriano-Campos JA, Huetzen MA, Goergens J, Jevtic M, Jahn-Kelleter HM, Zempel H, Placzek A, Hennrich AA, Conzelmann KK, Tumbrink HL, Hunold P, Isensee J, Werr L, Gaedke F, Schauss A, Minère M, Müller M, Fenselau H, Liu Y, Heimsoeth A, Gülcüler Balta GS, Walczak H, Frezza C, Jachimowicz RD, George J, Schmiel M, Brägelmann J, Hucho T, von Karstedt S, Peifer M, Annibaldi A, Hänsel-Hertsch R, Persigehl T, Grüll H, Sos ML, Reifenberger G, Fischer M, Adriaensen D, Büttner R, Sage J, Brouns I, Rad R, Thomas RK, Anstötz M, Rizzoli SO, Bergami M, Motori E, Reinhardt HC, Beleggia F. Functional synapses between neurons and small cell lung cancer. Nature. 2025 Oct;646(8087):1243-1253. doi: 10.1038/s41586-025-09434-9. Epub 2025 Sep 10.

2024

• Veli Ö, Kaya Ö, Varanda AB, Hildebrandt X, Xiao P, Estornes Y, Poggenberg M, Wang Y, Pasparakis M, Bertrand MJM, Walczak H, Annibaldi A, Cardozo AK, Peltzer N. RIPK1 is dispensable for cell death regulation in B-cells during hyperglycemia. Molecular Metab, Sept;87:101988. https://doi.org/10.1016/j.molmet.2024.101988
• Joy JD, Malacrida B, Laforêts F, Kotantaki P, Maniati E, Manchanda R, Annibaldi A, Hopkins S, Garrobo-Calleja I, Gautrot J, Balkwill FR. Human 3D Ovarian Cancer Models Reveal Malignant Cell-Intrinsic and -Extrinsic Factors That Influence CAR T-cell Activity. Cancer Res. 2024 Aug 1;84(15):2432-2449. doi: 10.1158/0008-5472.CAN-23-3007.

2023

• Lagunas KM, Savcigil DP, Zrilic M, Fraile CC, Craxton A, Self E, Uranga-Murillo I, de Miguel D, Arias M, Willenborg S, Piekarek M, Albert MC, Nugraha K, Lisewski I, Janakova E, Igual N, Tonnus W, Hildebrandt X, Ibrahim M, Ballegeer M, Saelens X, Kueh A, Meier P, Linkermann A, Pardo J, Eming S, Walczak H,  MacFarlane M, Peltzer N and Annibaldi A. Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair.Sci. Adv.9,eadg2829(2023).DOI:10.1126/sciadv.adg2829

2022

• Peltzer N, Annibaldi A.Cell Death-Related Ubiquitin Modifications in Inflammatory Syndromes: From Mice to Men.Biomedicines. 2022 Jun 17;10(6):1436. doi: 10.3390/biomedicines10061436.

2021

• Garcia LR, Tenev T, Newman R, Haich RO, Liccardi G, John SW, Annibaldi A, Yu L, Pardo M, Young SN, Fitzgibbon C, Fernando W, Guppy N, Kim H, Liang LY, Lucet IS, Kueh A, Roxanis I, Gazinska P, Sims M, Smyth T, Ward G, Bertin J, Beal AM, Geddes B, Choudhary JS, Murphy JM, Aurelia Ball K, Upton JW, Meier P. Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance. Nature Commun. 2021 Jun 7;12(1):3364. doi: 10.1038/s41467-021-23474-5.
• Heath O, Berlato C, Maniati E, Lakhani A, Pegrum C, Kotantaki P, Elorbany S, Böhm S, Barry ST, Annibaldi A, Barton DP, Balkwill FR.Chemotherapy Induces Tumor-Associated Macrophages that Aid Adaptive Immune Responses in Ovarian Cancer. Cancer Immunol Res. 2021 Jun;9(6):665-681. doi: 10.1158/2326-6066.CIR-20-0968. Epub 2021 Apr 10.

2020

• Annibaldi A, Walczak H. Death Receptors and Their Ligands in Inflammatory Disease and Cancer. Cold Spring Harb Perspect Biol. 2020 Jan 27. doi: 10.1101/cshperspect.a036384

2019

• Ruiz EJ, Diefenbacher ME, Nelson JK, Sancho R, Pucci F, Chakraborty A, Moreno P, Annibaldi A, Liccardi G, Encheva V, Mitter R, Rosenfeldt M, Snijders AP, Meier P, Calzado MA, Behrens A. LUBAC determines chemotherapy resistance in squamous cell lung cancer. J Exp Med. 2019 Feb 4;216(2):450-465. doi: 10.1084/jem.20180742. Epub 2019 Jan 14. PubMed PMID: 30642944; PubMed Central PMCID: PMC6363428.

2018 

• Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand AJ, Robertson D, Feltham R, Anderton H, Darding M, Peltzer N, Dannappel M, Schünke H, Fava LL, Haschka MD, Glatter T, Nesvizhskii A, Schmidt A, Harris PA, Bertin J, Gough PJ, Villunger A, Silke J, Pasparakis M, Bianchi K, Meier P. RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. Mol Cell. 2019 Feb 7;73(3):413-428.e7. doi: 10.1016/j.molcel.2018.11.010. Epub 2018 Dec 28. PubMed PMID: 30598363; PubMed Central PMCID: PMC6375735.
• Annibaldi A, Meier P. Ripk1 and haematopoiesis: a case for LUBAC and Ripk3. Cell Death Differ. 2018 Aug;25(8):1361-1363. doi: 10.1038/s41418-018-0135-2. PubMed PMID: 29867129; PubMed Central PMCID: PMC6113204.
• Feltham R, Jamal K, Tenev T, Liccardi G, Jaco I, Domingues CM, Morris O, John SW, Annibaldi A, Widya M, Kearney CJ, Clancy D, Elliott PR, Glatter T, Qiao Q, Thompson AJ, Nesvizhskii A, Schmidt A, Komander D, Wu H, Martin S, Meier P. Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential. Cell Rep.2018 Apr 10;23(2):470-484. doi: 10.1016/j.celrep.2018.03.054. PubMed PMID: 29642005; PubMed Central PMCID: PMC5912950.
• Annibaldi A, Wicky John S, Vanden Berghe T, Swatek KN, Ruan J, Liccardi G, Bianchi K, Elliott PR, Choi SM, Van Coillie S, Bertin J, Wu H, Komander D, Vandenabeele P, Silke J, Meier P. Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2. Mol Cell. 2018 Feb 15;69(4):566-580.e5. doi: 10.1016/j.molcel.2018.01.027. PubMed PMID: 29452637; PubMed Central PMCID: PMC5823975.

2017

• Annibaldi A, Meier P. Checkpoints in TNF-Induced Cell Death: Implications in Inflammation and Cancer. Trends Mol Med. 2018 Jan;24(1):49-65. doi: 10.1016/j.molmed.2017.11.002. Epub 2017 Dec 5. Review. PubMed PMID: 29217118.
• *Jaco I, Annibaldi A*, *Lalaoui N, *Wilson R, Tenev T, Laurien L, Kim C, Jamal K, Wicky John S, Liccardi G, Chau D, Murphy JM, Brumatti G, Feltham R, Pasparakis M, Silke J, Meier P. MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death. Mol Cell. 2017 Jun 1;66(5):698-710.e5. doi: 10.1016/j.molcel.2017.05.003. Epub 2017 May 11. PubMed PMID: 28506461; PubMed Central PMCID: PMC5459754. *shared authorship
• Tsoutsou P, Annibaldi A, Viertl D, Ollivier J, Buchegger F, Vozenin MC, Bourhis J, Widmann C, Matzinger O. TAT-RasGAP_317-326 Enhances Radiosensitivity of Human Carcinoma Cell Lines In Vitro and In Vivo through Promotion of Delayed Mitotic Cell Death. Radiat Res. 2017 May;187(5):562-569. doi: 10.1667/RR14509.1. Epub 2017 Mar 21. PubMed PMID: 28323576.